Topotecan Package Insert

HIGHLIGHTS OF PRESCRIBING INFORMATION - Novartis
HYCAMTIN® (topotecan) capsules, for oral use Initial U.S. Approval: 1996 HYCAMTIN is contraindicated in patients who have a history of severe hypersensitivity reactions to topotecan. Reactions have included anaphylactoid reactions [see Adverse Reactions (6.2)]. ... Read Content

HIGHLIGHTS OF PRESCRIBING INFORMATION ...
Topotecan-induced neutropenia can lead to neutropenic colitis. (5.2) • Interstitial lung disease: HYCAMTIN has been associated with reports of interstitial lung disease. Monitor patients for symptoms and discontinue HYCAMTIN if the diagnosis is confirmed. (5.3) • Pregnancy: Can cause fetal harm. Advise women of potential risk to the fetus. ... Retrieve Here

HYCAMTIN Initial U.S. Approval: 1996
Topotecan-induced neutropenia can lead to neutropenic colitis. Fatalities due to neutropenic colitis have been reported. In patients presenting with fever, neutropenia, and a compatible pattern of abdominal pain, the possibility of neutropenic colitis should be considered. ... Return Document

HYCAMTIN IV Prescribing Information - HemOnc.org
(topotecan hydrochloride) For Injection FOR INTRAVENOUS USE WARNING HYCAMTIN (topotecan hydrochloride) for Injection should be administered under the supervision of a physician experienced in the use of cancer chemotherapeutic agents. ... Fetch This Document

HIGHLIGHTS OF PRESCRIBING INFORMATION First-Line Non Squamous ...
Avastin, in combination with paclitaxel and cisplatin or paclitaxel and topotecan, is indicated for the treatment of patients with persistent, recurrent, or metastatic cervical cancer. 1.6 Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer ... Read Content

HIGHLIGHTS OF PRESCRIBING INFORMATION Limitation Of Use: The ...
3 FULL PRESCRIBING INFORMATION 1 INDICATIONS AND USAGE 1.1 Melanoma KEYTRUDA®(pembrolizumab) is indicated for the treatment of patients with unresectable or metastatic melanoma [see Clinical Studies (14.1)]. 1.2 Non-Small Cell Lung Cancer ... Return Doc

HIGHLIGHTS OF PRESCRIBING INFORMATION ...
2 FULL PRESCRIBING INFORMATION 1 INDICATIONS AND USAGE 1.1 Ovarian Cancer GEMZAR®in combination with carboplatin is indicated for the treatment of patients with advanced ovarian cancer that has relapsed at least 6 months after completion of platinum-based therapy. ... Retrieve Document

PACKAGE INSERT TEMPLATE FOR CARBOPLATIN SOLUTION FOR ...
PACKAGE INSERT TEMPLATE FOR CARBOPLATIN SOLUTION FOR INJECTION Brand or Product Name [Product name] Solution for Injection 10mg/ml Name and Strength of Active Substance(s) Concurrent use of topotecan and carboplatin may result in severe myelosuppression. ... Read More

Topotecan (alternate) - Mipedscompounds.org
2. Dilute topotecan 4 mg injection with 4 mL of sterile water, per package insert, to form a 1 mg/mL concentration 3. Draw up 28.5 mL of normal saline 4. Inject normal saline into an empty sterile 30 mL vial 5. Add topotecan to the sterile vial, mix solution gently 6. Draw up 30 mL from the vial via Phaseal and transfer to 2 ounce amber bottle 7. ... Content Retrieval

L'idarubicine ou 4-déméthoxydaunorubicine est un anticancéreux de type anthracycline.Elle s'insère dans l'ADN et l'empêche de se dérouler en interférant avec l'enzyme topoisomérase II.C'est un analogue de la daunorubicine, mais l'absence de groupe méthoxy accroît sa Liposolubilité et son absorption cellulaire [3]. ... Read Article

Topotecan - Mipedscompounds.org
Topotecan 4 mg injection 2 vials Sterile Water 8 mL Directions: 1. Use Phaseal to prepare stock vial 2. Per topotecan package insert, dilute each vial with 4 mL of sterile water for a final concentration of 1 mg/mL 3. After reconstitution of vial, gently mix solution 4. Transfer solution from each vial into a 2 ounce amber bottle 5. ... Get Doc

HIGHLIGHTS OF PRESCRIBING INFORMATION Interstitial Lung ...
HYCAMTIN FOR INJECTION safely and effectively. See full Topotecan can cause fatal typhlitis (neutropenic enterocolitis). Consider the possibility of typhlitis in patients . presenting with fever, neutropenia, and abdominal pain. ... Fetch Doc

Cytarabine Injection - Pfizer.com
Pharmacy Bulk Package. A Pharmacy Bulk Package is a container of a sterile preparation for parenteral use that contains many single doses. The contents are intended for use in a pharmacy admixture program and are restricted to the preparation of admixtures for intravenous infusion. ... Read Full Source

HIGHLIGHTS OF PRESCRIBING INFORMATION These Highlights Do Not ...
Tablets containing sorafenib tosylate (274 mg) equivalent to 200 mg of sorafenib. NEXAVAR tablets are round, biconvex, red film-coated tablets, debossed with the “Bayer cross” on one side and “200” on the other side. ... Return Doc

METHOTREXATE SCHEDULING STATUS: PROPRIETARY NAME (and Dosage ...
Approved Package Insert: 5 Jun 2013 Page 2of 30 Excretion of single daily doses occurs through the kidneys in amounts from 55% to 88% or higher within 24 hours. Repeated doses daily result in more sustained serum levels and some retention of methotrexate over each 24 hour period, which may result in accumulation of the medicine within the tissues. ... Retrieve Full Source

TAXOL (paclitaxel) INJECTION - HemOnc.org
TAXOL (paclitaxel) Injection is a clear, colorless to slightly yellow viscous solution. It is supplied as a nonaqueous solution intended for dilution with a suitable parenteral fluid prior to intravenous infusion. TAXOL is available in 30 mg (5 mL), 100 mg (16.7 mL), and 300 mg (50 mL) multidose vials. ... Fetch This Document

ToposarTM - Pfizer
TOPOSAR is contraindicated in patients who have demonstrated a previous hypersensitivity to it. WARNINGS Patients being treated with TOPOSAR must be frequently observed for myelosuppression both during and after therapy. Dose-limiting bone marrow suppression is the most significant toxicity associated with etoposide therapy. ... Doc Retrieval

Package Insert - Immunosuppression Thymoglobulin
Reconstitution After calculating the number of vials needed, using aseptic technique, reconstitute each vial of THYMOGLOBULIN with 5 mL of Sterile Water for Injection, USP (SWFI). ... Retrieve Here